2025

• Tsvetkov D, Meyer-Tönnies MJ, Tzvetkov MV, Weitschies W, Engeli S, Lebedeva A, Hannemann A, Jordan MC, Garscha U, Valentini L, Antonenko D, Kennes LN, Gollasch M. Effective Therapeutic Strategies to Prevent Frailty and Falls in Community-Dwelling Older Adults. Aging Dis. 2025 Jun 17. doi: 10.14336/AD.2025.0445.
• Bartz FM, Sałat K, Urbańska K, Lemke J, Rosendahl P, Schmidt L, Schulig L, Garscha U, Link A, Bednarski PJ. New K_V7.2/3 Channel Activators Exhibit Superior Toxicity and Metabolic Profiles to Flupirtine and Demonstrate Promising In Vivo Analgesic Effects. ACS Chem Neurosci. 2025 Jun 18;16(12):2322-2333. doi: 10.1021/acschemneuro.5c00278.
• Gollasch M, Kassmann M, Alves DT, Garscha U, Tsvetkov D. Metabolic Regulation of Vascular Smooth Muscle Potassium Channels by Perivascular Adipose Tissue. Arterioscler Thromb Vasc Biol. 2025 Jul;45(7):1031-1040. doi: 10.1161/ATVBAHA.125.321693.
• Schebb NH, Kampschulte N, Hagn G, Plitzko K, Meckelmann SW, Ghosh S, Joshi R, Kuligowski J, Vuckovic D, Botana MT, Sánchez-Illana Á, Zandkarimi F, Das A, Yang J, Schmidt L, Checa A, Roche HM, Armando AM, Edin ML, Lih FB, Aristizabal-Henao JJ, Miyamoto S, Giuffrida F, Moussaieff A, Domingues R, Rothe M, Hinz C, Das US, Rund KM, Taha AY, Hofstetter RK, Werner M, Werz O, Kahnt AS, Bertrand-Michel J, Le Faouder P, Gurke R, Thomas D, Torta F, Milic I, Dias IHK, Spickett CM, Biagini D, Lomonaco T, Idborg H, Liu JY, Fedorova M, Ford DA, Barden A, Mori TA, Kennedy PD, Maxey K, Ivanisevic J, Gallart-Ayala H, Gladine C, Wenk M, Galano JM, Durand T, Stark KD, Barbas C, Garscha U, Gelhaus SL, Ceglarek U, Flamand N, Griffin JL, Ahrends R, Arita M, Zeldin DC, Schopfer FJ, Quehenberger O, Julian R, Nicolaou A, Blair IA, Murphy MP, Hammock BD, Freeman B, Liebisch G, Serhan CN, Köfeler HC, Jakobsson PJ, Steinhilber D, Gelb MH, Holčapek M, Andrew R, Giera M, FitzGerald GA, Murphy RC, Newman JW, Dennis EA, Ekroos K, Milne GL, Gijón MA, Vesper HW, Wheelock CE, O'Donnell VB. Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry. Sci Signal. 2025 May 20;18(887):eadw1245. doi: 10.1126/scisignal.adw1245.
• Romp E, Rataj K, König S, Newcomer ME, Werz O, Garscha U. Modifications in FLAP's second cytosolic loop influence 5-LOX interaction, inhibitor binding, and leukotriene formation. FEBS Lett. 2025 May 8. doi: 10.1002/1873-3468.70066.
• Lemke J, Mengers N, Schmidt L, Schulig L, König S, Rosendahl P, Bartz FM, Garscha U, Bednarski PJ, Link A. Lead Optimization of Positive Allosteric K_V7.2/3 Channel Modulators toward Improved Balance of Lipophilicity and Aqueous Solubility. J Med Chem. 2025 Apr 24;68(8):8377-8399. doi: 10.1021/acs.jmedchem.4c03112.
• Li Z, Han X, Cong L, Singh P, Paiva P, Branson Y, Li W, Chen Y, Jaradat DMM, Lennartz F, Bayer T, Schmidt L, Garscha U, You S, Fernandes PA, Ramos MJ, Bornscheuer UT, Weber G, Wei R, Liu W. Structure-Guided Engineering of a Versatile Urethanase Improves Its Polyurethane Depolymerization Activity. Adv Sci (Weinh). 2025 Apr;12(13):e2416019. doi: 10.1002/advs.202416019.
• Schmidt L, Garscha U. Species-specific optimization of oxylipin ionization in LC-MS: a design of experiments approach to improve sensitivity. Anal Bioanal Chem. 2025 Apr;417(9):1807-1818. doi: 10.1007/s00216-025-05759-6.
• Branson Y, Liu J, Schmidt L, Griebel J, Prager A, Stieler L, Breite D, Bayer T, Besenmatter W, Dong W, Garscha U, Bornscheuer UT, Wei R. One-Pot Depolymerization of Mixed Plastics Using a Dual Enzyme System. ChemSusChem. 2025 May 5;18(9):e202402416. doi: 10.1002/cssc.202402416.
• Luna FG, Lupiáñez J, König S, Garscha U, Fischer R. Can transcutaneous auricular vagus nerve stimulation mitigate vigilance loss? Examining the effects of stimulation at individualized versus constant current intensity. Psychophysiology. 2025 Jan;62(1):e14670. doi: 10.1111/psyp.14670.

2024

• Tolksdorf C, Seidel A, Baume C, Moritz E, Saljé K, Lehmann K, Becker K, Garscha U, Thiele T, Schwedhelm E, von Lucadou M, Tzvetkov MV, Engeli S, Jedlitschky G, Rauch BH. Enhanced platelet sensitization is accompanied by increased expression of the transporter MRP4 and elevated plasma S1P levels in mild COVID-19 convalescents. Platelets. 2024 Dec;35(1):2413713. doi: 10.1080/09537104.2024.2413713.
• Bayer T, Palm GJ, Berndt L, Meinert H, Branson Y, Schmidt L, Cziegler C, Somvilla I, Zurr C, Graf LG, Janke U, Badenhorst CPS, König S, Delcea M, Garscha U, Wei R, Lammers M, Bornscheuer UT. Structural Elucidation of a Metagenomic Urethanase and Its Engineering Towards Enhanced Hydrolysis Profiles. Angew Chem Int Ed Engl. 2024 Sep 16;63(38):e202404492. doi: 10.1002/anie.202404492.
• Schimanski J, Gresnigt MS, Brunner E, Werz O, Hube B, Garscha U. Hyphal-associated protein expression is crucial for Candida albicans-induced eicosanoid biosynthesis in immune cells. Eur J Immunol. 2024 Mar;54(3):e2350743. doi: 10.1002/eji.202350743.

2023

• Schoenthaler M, Waltl L, Hasenoehrl T, Seher D, Lutz A, Aulinger L, Temml V, König S, Siller A, Braun DE, Garscha U, Werz O, Schuster D, Schennach H, Koeberle A, Matuszczak B. Novel thiazolopyridine derivatives of diflapolin as dual sEH/FLAP inhibitors with improved solubility. Bioorg Chem. 2023 Oct;139:106685. doi: 10.1016/j.bioorg.2023.106685.
• Teder T, König S, Singh R, Samuelsson B, Werz O, Garscha U, Haeggström JZ. Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A₄ Hydrolase. Int J Mol Sci. 2023 Apr 19;24(8):7539. doi: 10.3390/ijms24087539.

2022

• Schmidt L, Burmeister LS, Greinacher A, König S, Garscha U. Development of SFC-MS Method for Quantification of Eicosanoids Biosynthesized in Primary Human Blood Cells. Metabolites. 2022 Nov 30;12(12):1198. doi: 10.3390/metabo12121198.
• Tolksdorf C, Moritz E, Wolf R, Meyer U, Marx S, Bien-Möller S, Garscha U, Jedlitschky G, Rauch BH. Platelet-Derived S1P and Its Relevance for the Communication with Immune Cells in Multiple Human Diseases. Int J Mol Sci. 2022 Sep 7;23(18):10278. doi: 10.3390/ijms231810278.
• Vieider L, Zoeller E, Romp E, Schoenthaler M, Hernández-Olmos V, Temml V, Hasenoehrl T, Schuster D, Werz O, Garscha U, Matuszczak B. Synthesis and structure-activity relationships for some novel diflapolin derivatives with benzimidazole subunit. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1752-1764. doi: 10.1080/14756366.2022.2087645.
• Di Micco S, Terracciano S, Pierri M, Cantone V, Liening S, König S, Garscha U, Hofstetter RK, Koeberle A, Werz O, Bruno I, Bifulco G. Identification of 2,4-Dinitro-Biphenyl-Based Compounds as MAPEG Inhibitors. ChemMedChem. 2022 Nov 18;17(22):e202200327. doi: 10.1002/cmdc.202200327.

2021

• Fischer J, Gresnigt MS, Werz O, Hube B, Garscha U. Candida albicans-induced leukotriene biosynthesis in neutrophils is restricted to the hyphal morphology. FASEB J. 2021 Oct;35(10):e21820. doi: 10.1096/fj.202100516RR.